Overview
A lecture on mitochondria and cellular respiration that moves from the structure of the membranes and cristae to the Krebs cycle, the electron transport chain and ATP synthase. The lecturer explains why ATP synthase dimers fold the inner membrane, why complex II passes electrons without pumping protons, and how the proton gradient drives ATP production.
Outline
Membranes, matrix and cristae
- The outer membrane is permeable; respiration happens on the inner one.
- ATP synthase dimers bend the inner membrane into cristae.